Research Paper Volume 11, Issue 7 pp 1907—1917

Elevation of circular RNA circ_0005230 facilitates cell growth and metastasis via sponging miR-1238 and miR-1299 in cholangiocarcinoma

Figure 6. Circ_0005230 promotes cell growth and metastasis in vivo. (A) Tumors from nude mice after injection of transfected HuCCT1 cells. (B) Tumor volume was monitored every 3 days. (C) Ki67 expression and location were determined by IHC. (D) Lungs from experimental metastasis animal model of each group are shown. (E) HE staining was used to stain the resected lungs. (F) The number of tumor nodules on lung surfaces from two groups. *p<0.05, **p<0.01.