Research Paper Volume 11, Issue 6 pp 1874—1899

DNA methylation in genes of longevity-regulating pathways: association with obesity and metabolic complications

Figure 4. Methylation levels (beta values mean ± SEM) of CPGs located at genes of the longevity-regulating pathway in relation to Metabolic Syndrome categories after age and sex adjustments. Non-Metabolic syndrome vs Metabolic syndrome, p<0.05*; p<0.01**; p<0.001***; p<0.0001****. Metabolic syndrome was defined as the presence of three of five criteria: large waist circumference reduced HDL-c, hypertriglyceridemia, hypertension and fasting hyperglycemia.