Research Paper Volume 11, Issue 7 pp 2031—2044

Exogenous biological renal support ameliorates renal pathology after ischemia reperfusion injury in elderly mice

Figure 3. Exogenous biological renal support increased dedifferentiation in old IRI mice kidney. (A) The levels of Pax2, vimentin, and ERK1/2 in kidney extracts of the old IRI mice as measured by western blotting. Gels were performed under the same experimental conditions. (BD) Quantitative analyses of the band densities of Pax2, vimentin, and ERK1/2 expressions. Data are presented as means ± SDs. ▲P < 0.05, ▲▲P < 0.01 vs. O: sham; *P < 0.05, **P < 0.01 vs. O: IRI. SD, standard deviation.