Research Paper Volume 11, Issue 9 pp 2628—2652

Five miRNAs-mediated PIEZO2 downregulation, accompanied with activation of Hedgehog signaling pathway, predicts poor prognosis of breast cancer

Figure 2. Expression of PIEZO2 in breast cancer. (A) PIEZO2 expression in breast cancer cell lines (MCF-7, Bcap37, MDA-MB-468 and MDA-MB-231) compared with that in normal breast cell line (HBL-100); (B) PIEZO2 expression in clinical breast cancer tissues compared with that in matched adjacent normal tissues (n=16); (C) expression of PIEZO2 (also known as FAM38B) in breast cancer compared with normal controls by analyzing UALCAN database; (D) PIEZO2 protein expression level in breast cancer tissue and normal breast tissue was analyzed using immunohistochemical staining from HumanProteinAtlas database. *P<0.05. Errors bars indicate respective standard deviations.