Research Paper Volume 11, Issue 9 pp 2628—2652

Five miRNAs-mediated PIEZO2 downregulation, accompanied with activation of Hedgehog signaling pathway, predicts poor prognosis of breast cancer

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Figure 2.

Expression of PIEZO2 in breast cancer. (A) PIEZO2 expression in breast cancer cell lines (MCF-7, Bcap37, MDA-MB-468 and MDA-MB-231) compared with that in normal breast cell line (HBL-100); (B) PIEZO2 expression in clinical breast cancer tissues compared with that in matched adjacent normal tissues (n=16); (C) expression of PIEZO2 (also known as FAM38B) in breast cancer compared with normal controls by analyzing UALCAN database; (D) PIEZO2 protein expression level in breast cancer tissue and normal breast tissue was analyzed using immunohistochemical staining from HumanProteinAtlas database. *P<0.05. Errors bars indicate respective standard deviations.