Volume 11, Issue 9

15 May, 2019
pp 2542—2911

About the Cover

The cover features Figure 8 "Overall contribution of age to BPH pathogenic mechanisms. BPH/LUTD is a disease that occurs through the normal course of aging and often manifests clinically as bladder outlet obstruction (BOO)." from Liu et al.

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Table of Contents

Editorials

Aging and ischemic stroke

Mohammed Yousufuddin, Nathan Young,

https://doi.org/10.18632/aging.101931 pp 2542—2544

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Physical activity, CVD, and older adults

Richard A. Ferraro, Vincent A. Pallazola, Erin D. Michos,

https://doi.org/10.18632/aging.101942 pp 2545—2546

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MicroRNA Let-7 in B lymphocyte activation

Shuai Jiang, Wei Yan, Shizhen Emily Wang,

https://doi.org/10.18632/aging.101968 pp 2547—2548

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Acute coronary syndrome and postprandial delayed hyperchylomicronemia

Fumitaka Okajima, Osamu Kurihara, Masamichi Takano,

https://doi.org/10.18632/aging.101969 pp 2549—2550

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Research Papers

MiR-124 sensitizes cisplatin-induced cytotoxicity against CD133⁺ hepatocellular carcinoma cells by targeting SIRT1/ROS/JNK pathway

Yunxiuxiu Xu, Yu Lai, Hanqin Weng, Lanping Tan, Yanshan Li, Guangcheng Chen, Xingxi Luo, Yibiao Ye,

https://doi.org/10.18632/aging.101876 pp 2551—2564

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Modulation of Coenzyme Q₁₀ content and oxidative status in human dermal fibroblasts using HMG-CoA reductase inhibitor over a broad range of concentrations. From mitohormesis to mitochondrial dysfunction and accelerated aging

Fabio Marcheggiani, Ilenia Cirilli, Patrick Orlando, Sonia Silvestri, Alexandra Vogelsang, Anja Knott, Thomas Blatt, Julia M. Weise, Luca Tiano,

https://doi.org/10.18632/aging.101926 pp 2565—2582

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Long-term every-other-day administration of DMAMCL has little effect on aging and age-associated physiological decline in mice

Zhaomeng Sun, Lijun Zhao, Li Su, Qing Fang, Chenzhong Xu, Yuanyuan Su, Yao Liang, Guodong Li, Yanxue Xue, Tanjun Tong, Jun Chen,

https://doi.org/10.18632/aging.101932 pp 2583—2609

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A novel mRNA-miRNA-lncRNA competing endogenous RNA triple sub-network associated with prognosis of pancreatic cancer

Wenlong Wang, Weiyang Lou, Bisha Ding, Beng Yang, Hongda Lu, Qingzhi Kong, Weimin Fan,

https://doi.org/10.18632/aging.101933 pp 2610—2627

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Five miRNAs-mediated PIEZO2 downregulation, accompanied with activation of Hedgehog signaling pathway, predicts poor prognosis of breast cancer

Weiyang Lou, Jingxing Liu, Bisha Ding, Luqi Jin, Liang Xu, Xia Li, Jing Chen, Weimin Fan,

https://doi.org/10.18632/aging.101934 pp 2628—2652

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Prostate enlargement and altered urinary function are part of the aging process

Teresa T. Liu, Samuel Thomas, Dalton T. Mclean, Alejandro Roldan-Alzate, Diego Hernando, Emily A. Ricke, William A. Ricke,

https://doi.org/10.18632/aging.101938 pp 2653—2669

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Downregulation of miR-125b promotes resistance of glioma cells to TRAIL through overexpression of Tafazzin which is a mitochondrial protein

Wenjia Ma, Yan Cui, Min Liu, Zhigang Tan, Yugang Jiang,

https://doi.org/10.18632/aging.101939 pp 2670—2680

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Magnesium transporter protein solute carrier family 41 member 1 suppresses human pancreatic ductal adenocarcinoma through magnesium-dependent Akt/mTOR inhibition and bax-associated mitochondrial apoptosis

Jing Xie, Chien-shan Cheng, Xiao Yan Zhu, Ye Hua Shen, Li Bin Song, Hao Chen, Zhen Chen, Lu Ming Liu, Zhi Qiang Meng,

https://doi.org/10.18632/aging.101940 pp 2681—2698

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Laminin α4 overexpression in the anterior lens capsule may contribute to the senescence of human lens epithelial cells in age-related cataract

Yu Yan, Haiyang Yu, Liyao Sun, Hanruo Liu, Chao Wang, Xi Wei, Fanqian Song, Hulun Li, Hongyan Ge, Hua Qian, Xiaoguang Li, Xianling Tang, Ping Liu,

https://doi.org/10.18632/aging.101943 pp 2699—2723

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Rosiglitazone has a neutral effect on the risk of dementia in type 2 diabetes patients

Chin-Hsiao Tseng,

https://doi.org/10.18632/aging.101944 pp 2724—2734

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RON and RONΔ160 promote gastric cancer cell proliferation, migration, and adaption to hypoxia via interaction with β-catenin

Donghui Zhou, Ling Huang, Yong Zhou, Tao Wei, Lina Yang, Chao Li,

https://doi.org/10.18632/aging.101945 pp 2735—2748

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Male age: negative impact on sperm DNA fragmentation

Elena Albani, Stefano Castellano, Bruna Gurrieri, Luisa Arruzzolo, Luciano Negri, Elena M. Borroni, Paolo E. Levi-Setti,

https://doi.org/10.18632/aging.101946 pp 2749—2761

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MiR-191 inhibit angiogenesis after acute ischemic stroke targeting VEZF1

Kang Du, Can Zhao, Li Wang, Yue Wang, Kang-Zhen Zhang, Xi-Yu Shen, Hui-Xian Sun, Wei Gao, Xiang Lu,

https://doi.org/10.18632/aging.101948 pp 2762—2786

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The role of ORMDL3/ATF6 in compensated beta cell proliferation during early diabetes

Weixia Yang, Feifei Sheng, Baolan Sun, Shane Fischbach, Xiangwei Xiao,

https://doi.org/10.18632/aging.101949 pp 2787—2796

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Chondroprotective effects of platelet lysate towards monoiodoacetate-induced arthritis by suppression of TNF-α-induced activation of NF-ĸB pathway in chondrocytes

Li Yan, Li Zhou, Danting Xie, Wenxi Du, Fangming Chen, Qiang Yuan, Peijian Tong, Letian Shan, Thomas Efferth,

https://doi.org/10.18632/aging.101952 pp 2797—2811

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LINC00857 knockdown inhibits cell proliferation and induces apoptosis via involving STAT3 and MET oncogenic proteins in esophageal adenocarcinoma

Wenmei Su, Lihui Wang, Feiyu Niu, Lei Zou, Chunfang Guo, Zhuwen Wang, Xiao Yang, Jiancong Wu, Yi Lu, Jian Zhang, David G. Beer, Zhixiong Yang, Guoan Chen,

https://doi.org/10.18632/aging.101953 pp 2812—2821

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Phloretin protects against cardiac damage and remodeling via restoring SIRT1 and anti-inflammatory effects in the streptozotocin-induced diabetic mouse model

Yin Ying, Cheng Jiang, Meiling Zhang, Jiye Jin, Shuyu Ge, Xiaodong Wang,

https://doi.org/10.18632/aging.101954 pp 2822—2835

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Hepatic histopathology and apoptosis in diet-induced-obese mice under Escherichia coli pneumonia

Hetao Song, Zhicai Zuo, Zhuangzhi Yang, Caixia Gao, Kejie Chen, Jing Fang, Hengmin Cui, Ping Ouyang, Junliang Deng, Yi Geng, Hongrui Guo,

https://doi.org/10.18632/aging.101956 pp 2836—2851

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Poly(ADP-ribosyl)ation and DNA repair synthesis in the extracts of naked mole rat, mouse, and human cells

Anastasiya A. Kosova, Mikhail M. Kutuzov, Alexei N. Evdokimov, Ekaterina S. Ilina, Ekaterina A. Belousova, Svetlana A. Romanenko, Vladimir A. Trifonov, Svetlana N. Khodyreva, Olga I. Lavrik,

https://doi.org/10.18632/aging.101959 pp 2852—2873

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Metformin induces a fasting- and antifolate-mimicking modification of systemic host metabolism in breast cancer patients

Elisabet Cuyàs, Salvador Fernández-Arroyo, Maria Buxó, Sonia Pernas, Joan Dorca, Isabel Álvarez, Susana Martínez, Jose Manuel Pérez-Garcia, Norberto Batista-López, César A. Rodríguez-Sánchez, Kepa Amillano, Severina Domínguez, Maria Luque, Idoia Morilla, Agostina Stradella, Gemma Viñas, Javier Cortés, Sara Verdura, Joan Brunet, Eugeni López-Bonet, Margarita Garcia, Samiha Saidani, Jorge Joven, Begoña Martin-Castillo, Javier A. Menendez,

https://doi.org/10.18632/aging.101960 pp 2874—2888

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c-Met as a new marker of cellular senescence

Maria Boichuck, Jonathan Zorea, Moshe Elkabets, Marina Wolfson, Vadim E. Fraifeld,

https://doi.org/10.18632/aging.101961 pp 2889—2897

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miR-495 inhibits the growth of fibroblasts in hypertrophic scars

Bingyu Guo, Qiang Hui, Zhishan Xu, Peng Chang, Kai Tao,

https://doi.org/10.18632/aging.101965 pp 2898—2910

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Correction

Correction for: Accelerated DNA methylation age and the use of antihypertensive medication among older adults

Xu Gao, Elena Colicino, Jincheng Shen, Allan C. Just, Jamaji C. Nwanaji-Enwerem, Brent Coull, Xihong Lin, Pantel Vokonas, Yinan Zheng, Lifang Hou, Joel Schwartz, Andrea A. Baccarelli,

https://doi.org/10.18632/aging.101980 pp 2911

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