Aging-US is dedicated to advancing our understanding of the biological mechanisms that drive aging and the development of age-related diseases. Our mission is to serve as a platform for high-quality research that uncovers the cellular, molecular, and systemic processes underlying aging, and translates these insights into strategies to extend healthspan and delay the onset of chronic disease.
We aim to promote:
Aging-US actively welcomes studies that utilize innovative technologies, novel model systems, and early-phase clinical trials to accelerate the translation of aging research into meaningful interventions. By bridging fundamental biology with clinical application, the journal supports a paradigm shift from disease treatment to healthspan preservation.
Aging-US sincerely thanks all reviewers who contributed their expertise and time during 2025.
Rigorous and constructive peer review is essential to scientific progress. Through their careful evaluations, our reviewers played a central role in maintaining the scientific quality, integrity, and credibility of the journal...
-Marco Demaria
Editor-in-Chief, Aging-US

An epigenetic biomarker of aging for lifespan and healthspan
10.18632/aging.101414Effects of resveratrol, curcumin, berberine and other nutraceuticals on aging, cancer development, cancer stem cells and microRNAs
10.18632/aging.101250Longevity biotechnology: bridging AI, biomarkers, geroscience and clinical applications for healthy longevity
10.18632/aging.206135Effects of a natural ingredients-based intervention targeting the hallmarks of aging on epigenetic clocks, physical function, and body composition: a single-arm clinical trial
10.18632/aging.206221Sex-specific longitudinal reversal of aging in old frail mice
10.18632/aging.206304Theobromine is associated with slower epigenetic ageing
10.18632/aging.206344Systemic factors in young human serum influence in vitro responses of human skin and bone marrow-derived blood cells in a microphysiological co-culture system
10.18632/aging.206288Topical ABT-263 treatment reduces aged skin senescence and improves subsequent wound healing
10.18632/aging.206165Peto’s paradox’s relevance is off the scale
10.18632/aging.206258Identification and prognostic value of metabolism-related genes in gastric cancer
10.18632/aging.103838Brown adipose tissue enhances exercise performance and healthful longevity
10.18632/aging.206179DNA methylation GrimAge strongly predicts lifespan and healthspan
10.18632/aging.101684Infusion of blood from young and old mice modulates amyloid pathology
10.18632/aging.206319The role of phenylalanine and tyrosine in longevity: a cohort and Mendelian randomization study
10.18632/aging.206326