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2026 Press Releases

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Sex-Specific Hormones Could Hold the Key to Better Sarcopenia Treatments

07-13-2026

“ Sarcopenia, affecting over 60% of individuals above age 80, represents a critical challenge for aging populations worldwide. ” BUFFALO, NY — July 13, 2026 — A new review was published in Volume 18 of Aging on June 26, 2026, titled “ Hormonal dimorphism in sarcopenia disease .” The review was led by Romain Menard and…

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Multiple Biological Triggers Shape Cellular Senescence in Aging and Disease

07-07-2026

“ Cellular senescence is a stable form of cell-cycle arrest induced by diverse intrinsic and extrinsic stimuli. ” BUFFALO, NY — July 7, 2026 — A new review was published in Volume 18 of Aging on June 22, 2026, titled “ The multifaceted inducers of cellular senescence .” The review was led by first author Hilah Gal and…

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Comprehensive Individual-Patient Analysis Clarifies Life Expectancy Across Rare Progeria Disorders

07-06-2026

“ Classical laminopathic progeroid syndromes link nuclear-envelope defects to accelerated aging, but the specific prognosis for each subtype remains unclear .” BUFFALO, NY — July 6, 2026 — A new systematic review was published in Volume 18 of Aging on June 18, 2026, titled “ Life expectancy and causes of death in…

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Nonhuman Primate Research Reveals How Aging, Stress, and Behavior May Interact to Increase Disease Risk

07-01-2026

“ With age, the incidence of stress-related pathologies, in the etiopathogenesis of which endocrine dysfunctions play an important role, increases .” BUFFALO, NY — July 1, 2026 — A new review was published in Volume 18 of Aging on June 11, 2026, titled “ Age-related dysfunctions of the neuroendocrine axes in nonhuman…

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Cellular Senescence and Stem Cells Share a More Complex Relationship Than Previously Recognized

06-29-2026

“ Cellular senescence and stemness represent two biological entities with several opposing properties .” BUFFALO, NY — June 29, 2026 — A new review was published in Volume 18 of Aging on May 30, 2026, titled “ The love and hate relationship between cellular senescence and stemness .” The review was led by first author…

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Lifestyle Intervention Linked to Slower Biological Aging Markers in Older Men

06-25-2026

“ The intervention group exhibited a significant deceleration in DunedinPACE, corresponding to an estimated 2.2% slower pace of aging, whereas no meaningful change was observed in the control group .” BUFFALO, NY — June 25, 2026 — A new research paper was published in Volume 18 of Aging on May 29, 2026, titled “…

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Researchers Identify Key Signaling Pathway Driving Muscle Cell Aging

06-23-2026

“ Skeletal muscle displays an age-associated decline in motor function and muscle mass .” BUFFALO, NY — June 23, 2026 — A new research paper was published in Volume 18 of Aging on May 28, 2026, titled “ p38MAP kinase regulates senescence in human iPS-derived myocytes .” The study was led by first author Hiroki Sato…

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Childhood Adversity May Leave Lasting Biological Scars Decades Later

06-18-2026

“ Early-life adversity, particularly forced childhood migration, is associated with higher cardiometabolic risk and accelerated biological ageing in later life, emphasizing the long-term biological costs of social and political instability .” BUFFALO, NY — June 18, 2026 — A new research paper was published in Volume…

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Common Aging Mechanisms May Link Vision Loss Disorder to Increased Risk of Certain Cancers

06-16-2026

“ Neovascular age-related macular degeneration (nAMD) is a leading cause of vision loss in older adults and is increasingly recognized as a manifestation of systemic aging involving vascular and inflammatory pathways .” BUFFALO, NY — June 16, 2026 — A new research paper was published in Volume 18 of Aging on May 22,…

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Physics Meets Aging: Researchers Lay the Foundations of Gerophysics

06-11-2026

“ The goal is to build predictive models that bridge changes across biological scales: from subcellular to organism level, and timescales from cellular turnover to lifespan .” BUFFALO, NY — June 11, 2026 — A new meeting report was published in Volume 18 of Aging on May 14, 2026, titled “ Foundations of Gerophysics .”…

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Aging Muscle Follows Different Genetic Programs in Mice and Humans

06-10-2026

“ These findings caution against direct extrapolation of murine aging transcriptomics to human skeletal muscle biology, though select conserved pathways may represent viable cross-species targets for future investigation .” BUFFALO, NY — June 10, 2026 — A new research paper was published in Volume 18 of Aging on May…

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Thirty Years After the Discovery of SA-β-gal: Researchers Revisit the Hallmarks of Cellular Senescence

06-05-2026

“ Thirty years ago, the identification of activated beta-galactosidase during senescence led to one of the first characterizations of senescent cell accumulation during biological aging .” BUFFALO, NY — June 5, 2026 — A new review was published in Volume 18 of Aging on May 15, 2026, titled “ Blue period – features of…

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Senescent Muscle Cells Send Molecular Messages That May Contribute to Age-Related Muscle Decline

06-03-2026

“ Taken together, these results indicate that EVs and their miRNA cargo may be potential contributors to the SASP and senescence-associated signalling in skeletal muscle during advanced aging .” BUFFALO, NY — June 3, 2026 — A new research paper was published in Volume 18 of Aging-US on May 15, 2026, titled “…

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DNA Methylation Clocks May Help Explain How Social Inequality Influences Mortality

05-27-2026

“ Race, ethnicity, education, income, and occupation are important social factors affecting health and longevity .” BUFFALO, NY — May 27, 2026 — A new research paper was published in Volume 18 of Aging-US on May 8, 2026, titled “ The mediating role of DNA methylation clocks in associations of race, ethnicity,…

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Extending Healthspan Through Public Health and Longevity Medicine

05-20-2026

“ Instead, healthy longevity will likely depend on the coordinated integration of multiple intervention layers operating at different stages of the disease trajectory .” BUFFALO, NY — May 20, 2026 — A new editorial was published in Volume 18 of Aging-US on May 18, 2026, titled “ Public health in the age of longevity…

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Methylene Blue May Help Protect Hair Follicle Stem Cells from Aging and Metabolic Stress

05-19-2026

“Remarkably, pre-treatment with MB protected HFSCs from GLP-1 RA–induced metabolic stress and premature cell death.” BUFFALO, NY — May 19, 2026 — A new research paper was published in Volume 18 of Aging-US on May 5, 2026, titled “ Methylene blue protects hair follicle stem cells from oxidative and metabolic stress to…

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Precision Anti-Aging Strategies Aim to Target Harmful Senescent Cells While Preserving Beneficial Ones

05-15-2026

“ Accumulating evidence reveals that senescent cells are not merely deleterious pathological byproducts; rather, a subset plays indispensable physiological roles in embryonic development, wound healing, and the maintenance of tissue homeostasis . ” BUFFALO, NY — May 15, 2026 — A new review was published in Volume 18…

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Aging Immune Systems Show Reduced Ability to Clear Tuberculosis During Treatment

05-12-2026

“Immunosenescence increases susceptibility to infectious diseases like tuberculosis (TB) in older adults (≥60 years) and hinder effective containment of Mycobacterium tuberculosis (Mtb) during therapeutic intervention. ” BUFFALO, NY — May 12, 2026 — A new research paper was published in Volume 18 of Aging-US on May 4,…

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Large-Scale Multi-Omics Study Aims to Decode Aging in the Indian Population

05-07-2026

“ India is undergoing a rapid demographic transition, with its elderly population projected to exceed 347 million by 2050 . ” BUFFALO, NY — May 7, 2026 — A new research paper was published in Volume 18 of Aging-US on April 24, 2026, titled “ The BHARAT study: a multi-modal, multi-omics investigation of aging…

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Human Telomerase Shows Selective Cross-Species Activity, Revealing Limits of Animal Models

05-05-2026

“ Telomerase is a cellular enzyme that adds telomeric DNA sequences to the ends of chromosomes, aiding in preserving genome stability . ” BUFFALO, NY — May 5, 2026 — A new research paper was published in Volume 18 of Aging-US on April 13, 2026, titled “ Cross species activity of TERT human telomerase component .” The…

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Stage-Specific Gene Expression Changes Reveal Early Triggers of Cellular Aging

04-29-2026

“ Cellular senescence is a fundamental biological process that underlies organismal aging and age-related diseases; however, the temporal dynamics of gene expression during senescence remain unclear . ” Click here to listen to this press release . BUFFALO, NY — April 29, 2026 — A new research paper was published in…

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From Hydra to Rotifers: A New Hypothesis Explores Pathways to Delay Aging in Humans

04-27-2026

“ Hydra vulgaris (“Hydra”) exhibits negligible senescence due to continuous self-renewal and stem cell cycling, contrasting sharply with short-lived, eutelic rotifers that exhibit rapid aging and fixed somatic cell numbers post-development . ” Click here to listen to this press release . BUFFALO, NY — April 27, 2026 —…

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Epigenetic Aging Linked to MRI Signatures of Neurodegeneration but Not General Brain Aging

04-23-2026

“ Epigenetic clocks of biological aging have been associated with cognitive impairment and dementia . ” Click here to listen to this press release . BUFFALO, NY — April 23, 2026 — A new research paper was published in Volume 18 of Aging-US on April 7, 2026, titled “ Association of epigenetic age acceleration with MRI…

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Global Experts Highlight Path Toward Actionable Interventions in Human Aging

04-21-2026

“ The 12th Aging Research and Drug Discovery (ARDD) meeting convened at the University of Copenhagen, presenting a comprehensive overview of recent advancements in the biology of aging . ” Click here to listen to this press release . BUFFALO, NY — April 21, 2026 — A new meeting report was published in Volume 18 of…

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Modeling Premature Aging in Yeast Reveals Key Effects of Progerin on Cellular Lifespan

04-17-2026

“ The budding yeast, Saccharomyces cerevisiae, is an excellent model for studying mechanisms governing aging, with many genetic and biochemical pathways highly conserved . ” BUFFALO, NY — April 17, 2026 — A new research paper was published in Volume 18 of Aging-US on April 3, 2026, titled “ Modeling premature aging in…

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Gene–Phenotype Catalogue Provides New Insights into Premature Aging Disorders

04-15-2026

“ Progeroid syndromes (PS) are a heterogeneous group of rare hereditary disorders with features resembling premature aging . ” BUFFALO, NY — April 15, 2026 — A new research paper was published in Volume 18 of Aging-US on March 30, 2026, titled “ A manually curated gene–phenotype catalogue for progeroid syndromes and…

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ATF5 Required for Maintaining Mitochondrial Homeostasis and Skeletal Muscle Health During Aging

04-09-2026

“ With age, mitochondrial health and function become altered in muscle, but the role of ATF5 in regulating these processes has not yet been evaluated . ” BUFFALO, NY — April 9, 2026 — A new research paper was published in Volume 18 of Aging-US on March 27, 2026, titled “ ATF5 is required for the maintenance of…

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Small-Volume Hypertonic Saline Plus Furosemide Linked to Lower Inflammatory and Remodeling Markers in Acute Heart Failure

04-07-2026

“Our findings revealed that in subjects with ADHF, treatment with i.v. furosemide plus HSS significantly decreased the serum levels of IL-6, sST2, hsTnT, galectin-3, and NT-proBNP and modulated some miRNA expression.” BUFFALO, NY — April 7, 2026 — A new research paper was published in Volume 18 of Aging-US on March…

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BOLD Variability Modulation Linked to Age-Specific Bimanual Performance

04-02-2026

“Older adults exhibited higher BOLD SD in cerebellar lobule VIIIb and greater modulation across task conditions in both sensorimotor and cerebellar regions.” BUFFALO, NY — April 2, 2026 — A new research paper was published in Volume 18 of Aging-US on March 24, 2026, titled “ Age-specific relationship between the…

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Plant-Based Dietary Patterns Linked to Slower Epigenetic Aging

03-31-2026

“Following diets rich in plant foods and low in animal products may slow biological aging.” BUFFALO, NY — March 31, 2026 — A new research paper was published in Volume 18 of Aging-US on March 20, 2026, titled “ Plant-based dietary patterns are associated with slower epigenetic aging .” Led by first and corresponding…

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Exergames Could Improve Mood in Older Adults

03-25-2026

“No studies reported worsening mood, supporting exergames as a safe activity for this group.” BUFFALO, NY — March 25, 2026 — A new review was published in Volume 18 of Aging-US on March 18, 2026, titled “ What are the effects of exergames on the mood states of older people? A systematic review of experimental studies,…

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New Blood- and Microbiome-Based Neural Networks Forecast Human Biological Age

03-23-2026

“Both methods demonstrate high predictive accuracy (MAE ~ 6 years, R2 > 0.8) and the degree of agreement of assessments both with each other and with PhenoAge (correlation > 0.89).” BUFFALO, NY — March 23, 2026 — A new research paper was published in Volume 18 of Aging-US on March 12, 2026, titled “ Blood biochemical…

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Healthy Life Extension Positioned as Geroscience’s North Star

03-18-2026

“We should treat healthy life extension as the goal and define success as health-adjusted longevity: extending lifespan while proportionally expanding function, resilience, and independence.” BUFFALO, NY — March 18, 2026 — A new editorial was published in Volume 18 of Aging-US on March 10, 2026, titled “ Healthy life…

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Impact Journals to Participate at AACR Annual Meeting 2026 in San Diego

03-16-2026

Conference attendees are warmly invited to visit Booth 3641 to meet members of the Impact Journals team, discover notable recent publications, and discuss opportunities for collaboration. BUFFALO, NY – March 16, 2026 – Impact Journals (publisher of Aging-US ), is pleased to announce its participation as an exhibitor…

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BSO Recapitulates Anti-Obesity Effects of Sulfur Amino Acid Restriction Without Bone Loss

03-13-2026

“Sulfur amino acid restriction (SAAR), a diet low in methionine and lacking cysteine, reduces obesity but also lowers bone mineral density (BMD) and increases marrow adipose tissue.” BUFFALO, NY — March 13, 2026 — A new research paper was published in Volume 18 of Aging-US on March 2, 2026, titled “ D,…

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P38 MAPK Linked to Epigenetic Activation of Fibrotic Genes in Senescent Lung Fibroblasts

03-10-2026

“Pharmacological inhibition of p38 MAPK significantly reduced α-SMA and Col3A1 expression in both TGF-β1-stimulated fibroblasts and primary IPF cells.” BUFFALO, NY — March 10, 2026 — A new research paper was published in Volume 18 of Aging-US on March 3, 2026, titled “ P38 MAPK is involved in epigenetic regulation of…

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Next-Generation Metabolic Theory Suggests Glycolytic ATP Decline May Limit Lifespan

03-03-2026

“Glycolytic ATP production declines with age, contributing to common aging phenotypes such as reduced cell division and impaired DNA & mitochondria repair.” BUFFALO, NY — March 3, 2026 — A new research perspective was published in Volume 18 of Aging-US on February 24, 2026, titled “ A decline in glycolytic ATP…

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Study Identifies Opposing Roles for IL6 and IL6R in Long-Term Mortality

02-27-2026

“IL6 and IL6R appear to be biologically opposing causal regulators of human survival: IL6 increases, while IL6R reduces mortality through cardiovascular mechanisms.” BUFFALO, NY — February 27, 2026 — A new research paper was published in Volume 18 of Aging-US on February 6, 2026, titled “ Causal effects of…

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Study Identifies Aging-Associated Mitochondrial Circular RNAs

02-24-2026

“Here, we report profiles of circular RNAs annotated to mitochondrial chromosome, chrM, in young and old cohorts.” BUFFALO, NY — February 24, 2026 — A new research paper was published in Volume 18 of Aging-US on February 10, 2026, titled “ Aging-associated mitochondrial circular RNAs .” Led by first author Hyejin Mun…

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New Single-Cell Transcriptomic Clock Reveals Intrinsic and Systemic T Cell Aging in COVID-19 and HIV

02-19-2026

“These findings underscore the promise of single-cell transcriptomic biomarkers to disentangle the systemic and cell-intrinsic components of immune aging and to measure immune aging.” BUFFALO, NY — February 19, 2026 — A new research paper was published in Volume 18 of Aging-US on February 8, 2026, titled “ Single-cell…

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Polyploidy-Induced Senescence May Drive Aging, Tissue Repair, and Cancer Risk

02-18-2026

“Our work highlights the need to study polyploidy and senescence in concert to understand their roles in aging, cancer, and therapeutic resistance.” BUFFALO, NY — February 18, 2026 — A new editorial was published in Volume 18 of Aging-US on February 8, 2026, titled “ Polyploidy-induced senescence: Linking development,…

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How Aging Leads to Disease: New Two-Stage Model Explains Age-Related Illness

01-20-2026

“Here we propose a general account of how different determinants of aging can interact to generate late-life disease.” BUFFALO, NY — January 20, 2026 — A new review was published in Volume 17, Issue 12 of Aging-US on December 30, 2025, titled “ Aging as a multifactorial disorder with two stages .” “This article is a…

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Age-Related Changes in Sperm DNA May Play a Role in Autism Risk

01-16-2026

“Research findings suggest that advanced paternal age is associated with an increased risk of autism spectrum disorder (ASD) in children.” BUFFALO, NY — January 16, 2026 — A new research paper was published in Volume 17, Issue 12 of Aging-US on December 29, 2025, titled “ Age-specific DNA methylation alterations in…

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CD47 Antisense Therapy Improves Glucose Control and Lipid Balance in Aging Mice

01-15-2026

“Together, these findings support a beneficial role for CD47 knockdown in alleviating age-associated metabolic dysfunction through coordinated effects across multiple organs.” BUFFALO, NY — January 15, 2026 — A new research paper was published in Volume 17, Issue 12 of Aging-US on December 1, 2025, titled “ CD47…

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International Experts Connect Infections and Aging Through Cellular Senescence

01-07-2026

“Here we propose the concept of infection-driven senescence (IDS) to describe the phenomenon in which microbial agents, beyond viruses, can trigger cellular senescence in host cells.” Click here to listen to this press release BUFFALO, NY — January 7, 2026 — A new meeting report was published in Volume 17, Issue 12 of…

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RNA Splicing and Processing Emerge as Central Features of Human Aging Across Tissues

01-05-2026

“Our results demonstrate that differential connectivity analysis reveals significant transcriptional alterations that are not detected by differential expression analysis.” Click here to listen to the press release BUFFALO, NY — January 5, 2026 — A new research paper featured as the cover of Volume 17, Issue 12 of…

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