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Press Release Archive

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Stage-Specific Gene Expression Changes Reveal Early Triggers of Cellular Aging

04-29-2026

“ Cellular senescence is a fundamental biological process that underlies organismal aging and age-related diseases; however, the temporal dynamics of gene expression during senescence remain unclear . ” Click here to listen to this press release . BUFFALO, NY — April 29, 2026 — A new research paper was published in…

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From Hydra to Rotifers: A New Hypothesis Explores Pathways to Delay Aging in Humans

04-27-2026

“ Hydra vulgaris (“Hydra”) exhibits negligible senescence due to continuous self-renewal and stem cell cycling, contrasting sharply with short-lived, eutelic rotifers that exhibit rapid aging and fixed somatic cell numbers post-development . ” Click here to listen to this press release . BUFFALO, NY — April 27, 2026 —…

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Epigenetic Aging Linked to MRI Signatures of Neurodegeneration but Not General Brain Aging

04-23-2026

“ Epigenetic clocks of biological aging have been associated with cognitive impairment and dementia . ” Click here to listen to this press release . BUFFALO, NY — April 23, 2026 — A new research paper was published in Volume 18 of Aging-US on April 7, 2026, titled “ Association of epigenetic age acceleration with MRI…

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Global Experts Highlight Path Toward Actionable Interventions in Human Aging

04-21-2026

“ The 12th Aging Research and Drug Discovery (ARDD) meeting convened at the University of Copenhagen, presenting a comprehensive overview of recent advancements in the biology of aging . ” Click here to listen to this press release . BUFFALO, NY — April 21, 2026 — A new meeting report was published in Volume 18 of…

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Modeling Premature Aging in Yeast Reveals Key Effects of Progerin on Cellular Lifespan

04-17-2026

“ The budding yeast, Saccharomyces cerevisiae, is an excellent model for studying mechanisms governing aging, with many genetic and biochemical pathways highly conserved . ” BUFFALO, NY — April 17, 2026 — A new research paper was published in Volume 18 of Aging-US on April 3, 2026, titled “ Modeling premature aging in…

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Gene–Phenotype Catalogue Provides New Insights into Premature Aging Disorders

04-15-2026

“ Progeroid syndromes (PS) are a heterogeneous group of rare hereditary disorders with features resembling premature aging . ” BUFFALO, NY — April 15, 2026 — A new research paper was published in Volume 18 of Aging-US on March 30, 2026, titled “ A manually curated gene–phenotype catalogue for progeroid syndromes and…

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ATF5 Required for Maintaining Mitochondrial Homeostasis and Skeletal Muscle Health During Aging

04-09-2026

“ With age, mitochondrial health and function become altered in muscle, but the role of ATF5 in regulating these processes has not yet been evaluated . ” BUFFALO, NY — April 9, 2026 — A new research paper was published in Volume 18 of Aging-US on March 27, 2026, titled “ ATF5 is required for the maintenance of…

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Small-Volume Hypertonic Saline Plus Furosemide Linked to Lower Inflammatory and Remodeling Markers in Acute Heart Failure

04-07-2026

“Our findings revealed that in subjects with ADHF, treatment with i.v. furosemide plus HSS significantly decreased the serum levels of IL-6, sST2, hsTnT, galectin-3, and NT-proBNP and modulated some miRNA expression.” BUFFALO, NY — April 7, 2026 — A new research paper was published in Volume 18 of Aging-US on March…

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BOLD Variability Modulation Linked to Age-Specific Bimanual Performance

04-02-2026

“Older adults exhibited higher BOLD SD in cerebellar lobule VIIIb and greater modulation across task conditions in both sensorimotor and cerebellar regions.” BUFFALO, NY — April 2, 2026 — A new research paper was published in Volume 18 of Aging-US on March 24, 2026, titled “ Age-specific relationship between the…

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Plant-Based Dietary Patterns Linked to Slower Epigenetic Aging

03-31-2026

“Following diets rich in plant foods and low in animal products may slow biological aging.” BUFFALO, NY — March 31, 2026 — A new research paper was published in Volume 18 of Aging-US on March 20, 2026, titled “ Plant-based dietary patterns are associated with slower epigenetic aging .” Led by first and corresponding…

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Exergames Could Improve Mood in Older Adults

03-25-2026

“No studies reported worsening mood, supporting exergames as a safe activity for this group.” BUFFALO, NY — March 25, 2026 — A new review was published in Volume 18 of Aging-US on March 18, 2026, titled “ What are the effects of exergames on the mood states of older people? A systematic review of experimental studies,…

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New Blood- and Microbiome-Based Neural Networks Forecast Human Biological Age

03-23-2026

“Both methods demonstrate high predictive accuracy (MAE ~ 6 years, R2 > 0.8) and the degree of agreement of assessments both with each other and with PhenoAge (correlation > 0.89).” BUFFALO, NY — March 23, 2026 — A new research paper was published in Volume 18 of Aging-US on March 12, 2026, titled “ Blood biochemical…

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Healthy Life Extension Positioned as Geroscience’s North Star

03-18-2026

“We should treat healthy life extension as the goal and define success as health-adjusted longevity: extending lifespan while proportionally expanding function, resilience, and independence.” BUFFALO, NY — March 18, 2026 — A new editorial was published in Volume 18 of Aging-US on March 10, 2026, titled “ Healthy life…

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Impact Journals to Participate at AACR Annual Meeting 2026 in San Diego

03-16-2026

Conference attendees are warmly invited to visit Booth 3641 to meet members of the Impact Journals team, discover notable recent publications, and discuss opportunities for collaboration. BUFFALO, NY – March 16, 2026 – Impact Journals (publisher of Aging-US ), is pleased to announce its participation as an exhibitor…

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BSO Recapitulates Anti-Obesity Effects of Sulfur Amino Acid Restriction Without Bone Loss

03-13-2026

“Sulfur amino acid restriction (SAAR), a diet low in methionine and lacking cysteine, reduces obesity but also lowers bone mineral density (BMD) and increases marrow adipose tissue.” BUFFALO, NY — March 13, 2026 — A new research paper was published in Volume 18 of Aging-US on March 2, 2026, titled “ D,…

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P38 MAPK Linked to Epigenetic Activation of Fibrotic Genes in Senescent Lung Fibroblasts

03-10-2026

“Pharmacological inhibition of p38 MAPK significantly reduced α-SMA and Col3A1 expression in both TGF-β1-stimulated fibroblasts and primary IPF cells.” BUFFALO, NY — March 10, 2026 — A new research paper was published in Volume 18 of Aging-US on March 3, 2026, titled “ P38 MAPK is involved in epigenetic regulation of…

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Next-Generation Metabolic Theory Suggests Glycolytic ATP Decline May Limit Lifespan

03-03-2026

“Glycolytic ATP production declines with age, contributing to common aging phenotypes such as reduced cell division and impaired DNA & mitochondria repair.” BUFFALO, NY — March 3, 2026 — A new research perspective was published in Volume 18 of Aging-US on February 24, 2026, titled “ A decline in glycolytic ATP…

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Study Identifies Opposing Roles for IL6 and IL6R in Long-Term Mortality

02-27-2026

“IL6 and IL6R appear to be biologically opposing causal regulators of human survival: IL6 increases, while IL6R reduces mortality through cardiovascular mechanisms.” BUFFALO, NY — February 27, 2026 — A new research paper was published in Volume 18 of Aging-US on February 6, 2026, titled “ Causal effects of…

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Study Identifies Aging-Associated Mitochondrial Circular RNAs

02-24-2026

“Here, we report profiles of circular RNAs annotated to mitochondrial chromosome, chrM, in young and old cohorts.” BUFFALO, NY — February 24, 2026 — A new research paper was published in Volume 18 of Aging-US on February 10, 2026, titled “ Aging-associated mitochondrial circular RNAs .” Led by first author Hyejin Mun…

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New Single-Cell Transcriptomic Clock Reveals Intrinsic and Systemic T Cell Aging in COVID-19 and HIV

02-19-2026

“These findings underscore the promise of single-cell transcriptomic biomarkers to disentangle the systemic and cell-intrinsic components of immune aging and to measure immune aging.” BUFFALO, NY — February 19, 2026 — A new research paper was published in Volume 18 of Aging-US on February 8, 2026, titled “ Single-cell…

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