Research Paper Volume 11, Issue 9 pp 2699—2723

Laminin α4 overexpression in the anterior lens capsule may contribute to the senescence of human lens epithelial cells in age-related cataract

Figure 9. Summary of anterior lens capsular proteins and possible regulatory mechanism in age-related cataract (ARC). Schematic diagram of reactive oxygen species related senescent lens epithelial cells and senescent anterior lens capsules along with up-regulation of total LM, LMα4 and TGF-β1 and down-regulation of MMP-9.