Research Paper Volume 11, Issue 9 pp 2735—2748

RON and RONΔ160 promote gastric cancer cell proliferation, migration, and adaption to hypoxia via interaction with β-catenin

Figure 1. Correlation between RON and β-catenin in primary human gastric cancer tissues. (A) Scatter plot showing the correlation between RON/RONΔ160 and β-catenin levels in samples of human gastric cancer, paracancerous tissue and normal gastric tissue. (B) Relative expression of Wnt/β-catenin signaling pathways related genes in T, P and N were detected by qRT-PCR and normalized to GAPDH. (C) Representative Western blotting data of RON and Wnt signaling molecules in T, P and N. (D) Quantification of RON and Wnt signaling proteins in T, P and N. *, p<0.05; **, p<0.01 vs N. N: normal gastric tissue. P: paracancerous tissue; T: gastric cancer tissue.