Research Paper Volume 11, Issue 9 pp 2787—2796

The role of ORMDL3/ATF6 in compensated beta cell proliferation during early diabetes

Figure 5. ORMDL3 transcriptionally activates ATF6 in beta cells. An ATF6 Reporter Assay was applied to Min6 cells, using co-transfection of the reporter and ORMDL3, or siORMDL3 or Scr or empty. Luciferase activity was determined. *p<0.05. NS, no significance. N=5.