Research Paper Volume 11, Issue 9 pp 2898—2910

miR-495 inhibits the growth of fibroblasts in hypertrophic scars

Figure 5. miR-495 inhibits FAK in vivo (A) Comparison of initial area, average healing time and scar area after healing in each group. (B) Immunohistochemical staining showing expression of FAK in the control and miR-495 agomir groups (magnification: 100×). (C, D) Expression of FAK, FAKp-Tyr397, cyclin D1, bcl-2, bax, COL1A, TGF-β1 and α-SMA were detected using western blotting and real-time PCR. Data are presented as the mean ± SEM. ** P< 0.01