Research Paper Volume 11, Issue 10 pp 3348—3361

circFADS2 protects LPS-treated chondrocytes from apoptosis acting as an interceptor of miR-498/mTOR cross-talking

Figure 2. circFADS2 is upregulated in RA patients and LPS-treated chondrocytes. (A) qPCR analysis showing upregulated circFADS2 expression levels in RA patients. (B) qPCR analysis showed expression of IL-1β, TNF-α, and IL-17 in LPS-treated chondrocytes. (C) CircFADS2 levels were significantly augmented in LPS-treated chondrocytes when compared to the control group (non-treated cells). *P < 0.05, **P < 0.01 vs. the indicated group.