Research Paper Volume 11, Issue 12 pp 3900—3908

Mesenchymal stem cells rejuvenate cardiac muscle through regulating macrophage polarization

Figure 4. MSC-induced M2-polarization of macrophages is essential for reducing infarction area in MI-mice. (AB) Masson's trichrome staining to determine the fibrotic heart tissue, shown by gross images (A), by representative histological images (B), and by quantification (C). *p<0.05. N=5.