Research Paper Volume 11, Issue 12 pp 4032—4049

Long-time qingyan formula extract treatment exerts estrogenic activities on reproductive tissues without side effects in ovariectomized rats and via active ER to ERE-independent gene regulation

Figure 2. The effects of QYFE on index of uterine and adrenal gland, and sex hormone in circulation. The uterus index (A), adrenal gland index (B), serum levels of estradiol (E2) (C), luteinzing hormone (LH) (D) and follicle-stimulating hormone (FSH) (E) for OVX rats were measured at the end of the 12-week treatment period. Data are the mean and standard deviation (SD) of samples from 10 rats. P values are for the one-way analysis of variance (ANOVA). ***p < 0.001, compared with the sham group; #p < 0.05, ##p < 0.01, ###p < 0.001, compared with the OVX group.