Research Paper Volume 11, Issue 12 pp 4159—4182

Proteomics-based identification of different training adaptations of aged skeletal muscle following long-term high-intensity interval and moderate-intensity continuous training in aged rats


Figure 4. Expression of autophagy (A), apoptosis (B), and mitochondrial function markers (C), and adipocytokine signaling-related proteins (D). SED, sedentary; MICT, moderate-intensity continuous training; HIIT, high-intensity interval training; succinate dehydrogenase, SDH; sirtuin 3, SIRT3; aldehyde dehydrogenase 2, ALDH2; peroxisome proliferator-activated receptor γ coactivator-1Α, PGC-1a; adiponectin, ADP; autophagy-related gene-3, Atg-3; microtubule-associated protein 1 light chain 3 II, LC3-II; B-cell lymphoma 2, Bcl-2; Bcl-2-associated X protein, Bax; AMP-activated protein kinase, AMPK; adiponectin receptor 1, ADPR1; Forkhead box O1, FOXO1. Data were analyzed by one-way ANOVA followed by Tukey’s post-hoc and are presented as mean ± SD. * p < 0.05 vs. SED; ** p < 0.01 vs. SED; # p < 0.05 vs. MICT; ## p < 0.01 vs. MICT.