Research Paper Volume 11, Issue 14 pp 4876—4889

LncRNA SLCO4A1-AS1 promotes colorectal cancer cell proliferation by enhancing autophagy via miR-508-3p/PARD3 axis

Figure 5. SLCO4A1-AS1 regulated autophagy via PARD3. (A) LC3b after up- or down-regulation of SLCO4A1-AS1 in LOVO and HCT116 cells by Western blot analysis. (B) LC3b II expression was suppressed after SLCO4A1-AS1 knockdown; (C) LC3b I/II expression in SLCO4A1-AS1 stably-expressed LOVO and HCT116 cells after PARD3 depletion. (D) LC3b II expression in SLCO4A1-AS1-knowndown HT29 and SW620 cells was rescued after PARD3 restoration