Figure 4. Overexpression of FALEC significantly reduces tumor growth in vivo. (A) Tumors removed from the Nude mice 7 weeks after injection of SCC-9 and CAL-27 cells stably transfected with pcDNA-FALEC or pcDNA, respectively. (B) Average weight of tumors derived from each group. (C) The tumor growth of FALEC-overexpression and control cells grafted mice were measured every 7 days, tumor growth curve was calculated. Representative images of tumors of each group (n = 6). (D)The expression of FALEC in grafted tumor tissues was analyzed by RT-qPCR. (E) Representative images of IHC staining of the grafted tumor. Data are shown as means ± SD. *p< 0.05, **p < 0.01***p < 0.001.