Research Paper Volume 11, Issue 14 pp 4990—5007

Long noncoding RNA FALEC inhibits proliferation and metastasis of tongue squamous cell carcinoma by epigenetically silencing ECM1 through EZH2

Figure 6. FALEC suppress TSCC progression by downregulating ECM1. SCC-9 and CAL-27 cells transfected with pcDNA/pcDNA-FALEC/pcDNA-ECM1 and cells transfected with pcDNA-FALEC followed by transfection with pcDNA-ECM1. After transfection, the cells were analyzed by CCK-8 assays (A), EdU assays (B), Colony formation assays (C) and transwell assays (D). Data are shown as means ± SD. *p < 0.05, **p < 0.01, ***p < 0.001.