Research Paper Volume 11, Issue 14 pp 5035—5057

Overexpression of KLF5 is associated with poor survival and G1/S progression in pancreatic cancer

Figure 5. KLF5-targeted microRNAs in the pancreatic cancer pathway. In the pancreatic cancer pathway extracted from the KEGG PATHWAY database (http://www.genome.jp/kegg/pathway.html), 12 microRNAs activated by KLF5 inhibit Smad4, p53, p16 and BRCA2.