Research Paper Volume 11, Issue 14 pp 5215—5231

Profiling of mRNA of interstitial fibrosis and tubular atrophy with subclinical inflammation in recipients after kidney transplantation

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Figure 2. Validation of DEGs. (A) A total of 15 common DEGs were up-expressed or down-expressed simultaneously in both databases; (B) PCA analysis found that the contribution degrees of 10 DEGs, including EVI2B, CYTIP, GZMK, CD2, IRF8, IL7R, CD52, NLRC3, GZMA, and CCL5, were all > 0.9; (C) In those 10 genes, MCODE scores of CD2, IL7R, and CCL5 were all > 3 and the numbers of their nodes were all > 4.