**Figure 7.** **Circ-APC is a promising diagnostic and prognostic biomarker in DLBCL.** (**A**) qRT-PCR analysis of circ-APC expression in 80 pairs of DLBCL and adjacent normal tissues. (**B**) qRT-PCR analysis of circ-APC expression in plasma from 16 healthy controls and 27 DLBCL patients. (**C**) Receiver operating characteristic curve analysis on the diagnostic utility of plasma circ-APC in DLBCL. (**D**) Kaplan-Meier plot displaying patients’ overall survival based on the median circ-APC level in 80 DLBCL tissues. (**E**, **F**) qRT-PCR analysis of *APC* expression in DLBCL cell lines and tissues. (**G**) The correlation between circ-APC and *APC* expression in DLBCL tissues. ***p* < 0.01, ****p* < 0.001.