**Figure 4.** Apoptotic effects of Aβ peptides (10 µM, 20 h) on Neuro-2a (**A**) cells and Ate1 knockout Neuro-2a cells (**B**). The Annexin-V positive and PI negative cells were considered early apoptotic. Each value is expressed as a percentage of the total number of cells ± SD. The experiments were performed three times in triplicates; *p < 0.01, **p < 0.001.