Research Paper Volume 11, Issue 16 pp 6134—6152

Beta-amyloid induces apoptosis of neuronal cells by inhibition of the Arg/N-end rule pathway proteolytic activity

Figure 4. Apoptotic effects of Aβ peptides (10 µM, 20 h) on Neuro-2a (A) cells and Ate1 knockout Neuro-2a cells (B). The Annexin-V positive and PI negative cells were considered early apoptotic. Each value is expressed as a percentage of the total number of cells ± SD. The experiments were performed three times in triplicates; *p < 0.01, **p < 0.001.