Research Paper Volume 11, Issue 16 pp 6199—6216

Attenuated BK channel function promotes overactive bladder in a rat model of obesity

Figure 5. NS1619-induced STOCs are significantly attenuated in HFD DSM cells. Original recordings illustrating the effects of 30 μM NS1619 on STOCs in ND. (A) and HFD (B) DSM cells. (C) Summary data illustrating the differences in STOCs in the presence and absence of 30 μM NS1619 in ND and HFD DSM cells. Data are expressed as the mean ± SEM; n = 7, N = 5 per group; * P < 0.05 for ND vs. HFD; # P < 0.05 for control vs. NS1619. ND: normal diet; HFD: high-fat diet; STOCs: spontaneous transient outward currents; NS: not significant; Amp: amplitude; Freq: frequency.