Research Paper Volume 11, Issue 16 pp 6252—6272

Prognostic value of preoperative hematological markers combined with molecular pathology in patients with diffuse gliomas

Figure 2. Kaplan-Meier survival curves of glioma subgroups based on hematological markers. Lower-grade gliomas: (A) NLR > 2.00 is associated with worse OS (P < 0.001); (B) PLR > 169.23 is associated with worse OS (P = 0.013); (C) MLR > 0.34 is associated with worse OS (P = 0.046); and (D) AGR > 1.79 is associated with better OS (P = 0.043). (E) In Grade IV glioma, NLR > 7.25 is associated with better OS (P = 0.001). (F, G) In the IDH and TERT mutations group of lower-grade gliomas, NLR > 2.00 and MLR > 0.29 predict worse OS (P < 0.009 and P = 0.006, respectively). (H, I) In the IDH mutation only group of lower-grade gliomas, NLR > 2.18 and PLR > 164.00 predict worse OS (P = 0.047 and P = 0.014, respectively). (J, K) In the TERT mutation only group of lower-grade gliomas, NLR > 3.36 and PLR > 165.65 predict worse OS (P = 0.005 and P = 0.001, respectively). (L) In triple-negative lower-grade gliomas, NLR > 1.64 predicts worse OS.