Research Paper Volume 11, Issue 16 pp 6469—6489

Identification and validation of four hub genes involved in the plaque deterioration of atherosclerosis

Figure 1. Dataset selection flow chart and analysis processes. (A) In total, 136 datasets from Gene Expression Omnibus (GEO) and 94 datasets from ArrayExpress were evaluated. Finally, 4 datasets for mRNAs were selected for inclusion in the comprehensive analysis. (B) The present study consisted of 5 steps, and the results of the analysis were finally validated on clinical samples.