Research Paper Volume 11, Issue 16 pp 6469—6489

Identification and validation of four hub genes involved in the plaque deterioration of atherosclerosis

Figure 5. Linear regression analyses and ROC curve in training and poor prognosis sets. (A, C) The correlations of the expression of the 4 hub genes with AS state and advanced stage by linear regression analysis. (B, D) ROC curves of the 4 common hub genes for diagnosing the AS state or the advanced stage. According to one arbitrary guideline [31], we distinguished among excellent accuracy (0.9 ≤ AUC < 1), good accuracy (0.8 ≤ AUC < 0.9) and noninformative accuracy (AUC = 0.5).