Figure 2. Identification of a four-miRNA signature was significantly associated with OS of CRC patients in the training cohort. (A–C) Risk score distribution, survival status, and miRNA expression patterns for patients in high-risk and low-risk groups by the miRNA signature. (D) Kaplan-Meier curve analysis of OS of CRC patients in high-risk and low-risk groups. (E) Time-dependent ROC curves analysis. We used AUCs at 3 and 5 years to assess the prognostic accuracy, and calculated P values using the log-rank test.