Research Paper Volume 11, Issue 19 pp 8085—8102

Oxidative stress-induced cellular senescence desensitizes cell growth and migration of vascular smooth muscle cells through down-regulation of platelet-derived growth factor receptor-beta

Figure 5. Bioinformatics prediction of putative transcription factor-binding sites (TFBSs) on the platelet-derived growth factor receptor (PDGFR)-β promoter. The putative TFBSs were analyzed on the PDGFR-β promoter region (-529 to -1). The sequence of the PDGFR-β promoter is presented as white text on a black background. The locations of the predicted TFBS are labeled below the PDGFR-β promoter sequence. Transcriptional start site was defined as the +1 position.