Figure 6. Knockdown of Gal-1 reverses SNHG22-induced EOC chemotherapy resistance. (A) Gal-1 expression in EOC cells was modified by CRISPR/Cas9. (B) SNHG22 expression in Gal-1-knockdown EOC cells was modified by cDNA transfection. (C and D) Cisplatin or paclitaxel sensitivity was measured using CCK-8 assays in Gal-1 knockdown EOC cells. (E) Working model: The forced expression of SNHG22 facilitates the chemotherapy resistance of EOC cells. Data are presented as the means ± SDs in three independent experiments. **P < 0.01.