Research Paper Volume 11, Issue 19 pp 8239—8253

The long non-coding RNA, urothelial carcinoma associated 1, promotes cell growth, invasion, migration, and chemo-resistance in glioma through Wnt/β-catenin signaling pathway

Figure 8. UCA1 up-regulated in glioma tissues and correlated with poor clinical outcomes in patients with glioma. (A) The expression of UCA1 in glioma tissues (n = 64) and adjacent normal brain tissues (n = 64) determined by qRT-PCR. (B) The expression of UCA1 in glioma tissues from patients with tumor grade I (n = 18), grade II (n = 17), grade III (n = 16), and grade IV (n = 13) was measured by qRT-PCR. (C) The expression of UCA1 in every glioma tissue was determined by qRT-PCR. (D) The overall survival of glioma patients with low or high expression of UCA1 in glioma tissues were assessed by Kaplan-Meier survival analysis. Significant differences compared to control group were expressed as *P<0.05 and **P<0.01.