Research Paper Volume 11, Issue 19 pp 8433—8462

Brain pyrimidine nucleotide synthesis and Alzheimer disease

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Figure 5. Expression of genes encoding (A) DHODH and (B) UCK2 proteins from both pyrimidine nucleotide synthesis pathways. GAPDH mRNA levels have been used to normalize. CA1: hippocampal cornus ammon 1; EC: entorhinal cortex; DG: dentate gyrus; LC: locus ceruleus. Points represent individual samples and horizontal lines indicate mean ± standard deviation values. P values for Kruskal-Wallis tests are indicated under the graphs. Horizontal red lines indicate between-regions p values (p < 0.0083) fulfilling the post-hoc Bonferroni/Dunn criteria.