Research Paper Volume 11, Issue 19 pp 8542—8555

Probucol, a “non-statin” cholesterol-lowering drug, ameliorates D-galactose induced cognitive deficits by alleviating oxidative stress via Keap1/Nrf2 signaling pathway in mice

Figure 5. Effect of Prob on SOD, GSH-PX and HO-1 expression. (AC) SOD, GSH-PX and HO-1 mRNA expression, respectively. (DF) SOD, GSH-PX and HO-1 protein expression, respectively. Data in each experiment represent mean ± SEM from 10 independent samples. Statistically significant differences were calculated by one-way ANOVA using the SPSS 20.0 software. ** P<0.01, versus D-gal group.