Research Paper Volume 11, Issue 19 pp 8556—8572

Conserved aging-related signatures of senescence and inflammation in different tissues and species

Figure 3. Differentially expressed genes during tissue aging and associated biological processes. The upper part shows the number of identified differentially expressed genes (DEGs) within all three age comparisons (early aging, late aging, longevity) in every investigated species and tissue. The lower part shows for every comparison the dominant biological processes as determined by the majority of the annotated functions of the respective DEGs. Note that in some comparisons only few DEGs could be identified and hence may only poorly reflect the underlying age-related processes (n.d. – no data). For detailed information, see Supplementary Data 6 and Supplementary Data 11.