Research Paper Volume 11, Issue 19 pp 8573—8586

High body mass index, brain metabolism and connectivity: an unfavorable effect in elderly females

Figure 2. Gender-specific ROI-based correlations between BMI levels and regional metabolism. Graph shows significant correlations between BMI levels (x axis) and average SPM-T values of glucose metabolism in a series of a priori selected ROIs (y axis), in the female cohort. Positive SPM-T values indicate higher-than-average brain glucose metabolism in each ROI, as obtained through comparison with a reference control sample [see text]. Higher BMI levels are associated with increased glucose metabolism. Only ROIs where correlation is significant after Bonferroni correction are shown. Gray shaded areas represent confidence intervals for the regression line slope.