Research Paper Volume 11, Issue 19 pp 8587—8603

A molecular sub-cluster of colon cancer cells with low VDR expression is sensitive to chemotherapy, BRAF inhibitors and PI3K-mTOR inhibitors treatment

Figure 7. The VDR and CDX2 mediated transcriptional networks. (A) Spearman correlation between VDR and CDX2 expression in GSE17536, GSE24551 and GSE39582 datasets derived from primary colon cancer patients. (B) VDR and CDX2 mediated regulatory gene networks were created by cytoscape. First neighbor genes connected with VDR or CDX2 were demonstrated.