Research Paper Volume 11, Issue 19 pp 8642—8663

Decreased levels of circulating trimethylamine N-oxide alleviate cognitive and pathological deterioration in transgenic mice: a potential therapeutic approach for Alzheimer’s disease

Figure 6. Effects of 3,3-Dimethyl-1-butanol (DMB) on circulating TMAO levels in the plasma of WT and APP/PS1 mice. ***P<0.001, versus the WT+ NT mice, ##P<0.01, ###P<0.001, versus the APP/PS1+ NT mice, $$$P<0.001, versus the APP/PS1+DMB mice by one-way ANOVA analysis followed by Dunnett’s post hoc test. All values are means ± S.D. n=10. NT means no treatment.