Research Paper Volume 11, Issue 22 pp 10016—10030

Silencing of long non-coding RNA H19 downregulates CTCF to protect against atherosclerosis by upregulating PKD1 expression in ApoE knockout mice

Figure 1. High expression of H19 is found in AS aortic tissues. (A) The expression pattern of H19 in normal and AS aortic tissues determined by RT-qPCR. * p < 0.05 vs. the control group. The data were measurement data and expressed by mean ± standard deviation. Data differences between two groups were analyzed by unpaired t-test. n = 6. (B) The subcellular localization of H19 detected by FISH assay (× 400). The experiment was repeated three times independently.