Research Paper Volume 11, Issue 23 pp 10814—10825

Long noncoding RNA LINC00958 accelerates the proliferation and matrix degradation of the nucleus pulposus by regulating miR-203/SMAD3

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Figure 1. LncRNA LINC00958 was upregulated in degenerative NP samples. (A) The expression of LINC00958 was determined in 20 degenerative NP tissues and 10 scoliotic NP samples by using qRT-PCR analysis. (B) LINC00958 expression increased gradually along with the grade of exacerbation of disc degeneration. Data were showed as mean±SD. *p<0.05, **p<0.01 and ***p<0.001. U6 was used as the internal control.