Research Paper Volume 11, Issue 23 pp 10814—10825

Long noncoding RNA LINC00958 accelerates the proliferation and matrix degradation of the nucleus pulposus by regulating miR-203/SMAD3

Figure 1. LncRNA LINC00958 was upregulated in degenerative NP samples. (A) The expression of LINC00958 was determined in 20 degenerative NP tissues and 10 scoliotic NP samples by using qRT-PCR analysis. (B) LINC00958 expression increased gradually along with the grade of exacerbation of disc degeneration. Data were showed as mean±SD. *p<0.05, **p<0.01 and ***p<0.001. U6 was used as the internal control.