Review Volume 12, Issue 1 pp 996—1010

Long non-coding RNA RNF7 promotes the cardiac fibrosis in rat model via miR-543/THBS1 axis and TGFβ1 activation

Figure 3. Differentially-expressed lncRNAs in CF and normal rat hearts. (A) Hierarchical clustering of differentially-expressed lncRNAs in CF and normal rat hearts. (B) Co-expression network (lncRNA/ECM receptor interaction) between differentially-expressed lncRNAs and extracellular matrix (ECM) receptors, including Itga11, Col2a1, Tnr, Thbs4, Thbs1, Sv2c, and Comp, was established by Pearson’s correlation analysis. (R > 0.8, p < 0.05).