Research Paper Volume 11, Issue 22 pp 10422—10453

Large-scale analyses identify a cluster of novel long noncoding RNAs as potential competitive endogenous RNAs in progression of hepatocellular carcinoma

Figure 5. Pearson correlation analysis for six key lncRNAs with their associated miRNA and mRNAs in 366 HCC patients from TCGA. Pearson correlograms of lncRNA-miRNA paris (A), lncRNA-mRNA pairs (B) and mRNA-miRNA pairs (C) in upregulated lncRNAs including GBAP1, MCM3AP-AS1 and SLC16A1-AS1. lncRNA-miRNA paris (D), lncRNA-mRNA paris (E) and mRNA-miRNA paris (F) in downregulated lncRNAs including C3P1, HNF4A-AS1 and DIO3OS by Pearson correlation analysis. The correlation coefficient R value ranges from -1 to 1, the color of which changes from blue to brown.