Research Paper Volume 11, Issue 22 pp 10664—10683

Competing endogenous network analysis identifies lncRNA Meg3 activates inflammatory damage in UVB induced murine skin lesion by sponging miR-93-5p/epiregulin axis

Figure 3. (A) H&E staining of murine dorsal skin samples with or without UVB irradiation (scale bar = 100 μm). (B) Quantification of Meg3 expression by qRT-PCR in normal and UVB irradiated murine dorsal skin tissues. (C) Fluorescence in situ hybridization (FISH) of Meg3 in normal and UVB irradiated murine dorsal skin tissues. (D) Quantification of Meg3 expression by qRT-PCR after different exposure time of UVB irradiation. (E) Quantification of secreted MMP1 and MMP3 by ELISA in normal and UVB irradiated murine dorsal skin tissues. (F) The expression level of Ereg, MMP1, MMP3 by WB in normal and UVB irradiated murine dorsal skin tissues. (G) Quantification of miR-93-5p expression by qRT-PCR in normal and UVB irradiated murine dorsal skin tissues.