Research Paper Volume 11, Issue 22 pp 10711—10722

p62-DNA-encoding plasmid reverts tumor grade, changes tumor stroma, and enhances anticancer immunity

Figure 4. Effect of p62 plasmid on the growth of B16 melanoma in Wt and immunodeficient (SCID) mice. While the p62 plasmid inhibited tumor growth in wt mice, no effect was found in immunodeficient mice. Wt + p62 vs Wt: day14, p = 0.008; day16, p=0.02; day18, p =0.01 SCID +p62 vs SCID: day 14, p=0.40; day 16, p=0.31; day18, p=0.37.