Research Paper Volume 11, Issue 23 pp 10939—10951

Metabolically healthy obesity reduces the risk of Alzheimer’s disease in elders: a longitudinal study

Figure 3. Adjusted for age, sex, APOE Ɛ4 status, cognitive diagnosis, education, tobacco and alcohol use, and low-density lipoprotein cholesterol, compared to MHNW group, MHO group had higher CSF-Aβ concentrations(P=0.015) (A) on the baseline as well as larger whole brain volumes(P=0.004) (B) and hippocampal volumes (P=0.011) (C) after additional correction for the intracranial volume. Abbreviations: MHNW, metabolically healthy normal weight; MHO, metabolically healthy overweight/obese; CSF, cerebrospinal fluid; Aβ, Amyloid β.