Figure 1. Mangiferin reduces atherosclerotic lesion formation in apoE-/- mice. Eight-week-old male apoE-/- mice were intraperitoneally injected with PBS or mangiferin (15 mg/kg) every day for 12 weeks. (A–B) Representative image of Oil Red O staining of an aortic lesion. Original magnification: 40×. (C) Quantification of the lesion areas of mice (n=15/group). *P < 0.05 vs. control group. Values are expressed as the mean ± SEM (n =15/group). (D–E) Representative HE staining of an aortic lesion in apoE-/- mice. Original magnification: 40×.