Figure 1. Reactive oxygen species biosynthetic processes were significantly elevated in recurrent GBM. (A) Significantly elevated biological functions in recurrent GBM. pGBM represents primary GBM and rGBM represents recurrent GBM. *p<0.05, **p<0.01, ***p<0.001. (B) AUC values of recurrent GBM enriched biological functions in TCGA and CGGA databases. (C) The most representative genes were obtained by LASSO-COX dimensionality analysis of ROS related genes. (D) The lambda value of 6 most representative genes.