Research Paper Volume 11, Issue 23 pp 11010—11029

Reactive oxygen species metabolism-based prediction model and drug for patients with recurrent glioblastoma

Figure 1. Reactive oxygen species biosynthetic processes were significantly elevated in recurrent GBM. (A) Significantly elevated biological functions in recurrent GBM. pGBM represents primary GBM and rGBM represents recurrent GBM. *p<0.05, **p<0.01, ***p<0.001. (B) AUC values of recurrent GBM enriched biological functions in TCGA and CGGA databases. (C) The most representative genes were obtained by LASSO-COX dimensionality analysis of ROS related genes. (D) The lambda value of 6 most representative genes.