Research Paper Volume 11, Issue 23 pp 11054—11072

EGFR-specific CAR-T cells trigger cell lysis in EGFR-positive TNBC

Figure 5. TNBC cell lysis assay. (A) HS578T, (B) MDA-MB-468, and (C) MDA-MB-231 cells were labeled with YOYO-3 (red). Non-transduced T cells, con-CAR-T cells, EGFR-CAR-1 T cells, and EGFR-CAR-2 T effector cells were co-cultured with target cells at an E:T ratio of 10:1 for 24h.