Research Paper Volume 11, Issue 23 pp 11124—11135

JAK1 as a prognostic marker and its correlation with immune infiltrates in breast cancer

Figure 2. Kaplan-Meier survival curves comparing the high and low expression of JAK1 in breast cancer. In the Kaplan-Meier plotter database, high JAK1 expression was correlated with good. (A) RFS (HR[95% CI] = 0.75[0.67-0.85], P = 3e-06) (B) DMFS (HR[95% CI] = 0.6[0.49-0.74], P = 1.4e-06) and (C) OS (HR[95% CI] = 0.52[0.42-0.65], P = 1.5e-09). In TCGA data, high JAK1 expression was also correlated with good OS. (D) All breast cancers (P = 0.0030), (E) TNM I-II (P = 0.038) (F) TNM III-IV (P = 0.013).