Research Paper Volume 11, Issue 23 pp 11170—11185

Identification of differentially expressed genes in non-small cell lung cancer

Figure 6. Association of TOP2A, SLC2A1, TPX2, and ASPM with overall survival in patients with lung cancer. Survival analyses were conducted using the Kaplan Meier plotter tool. (A) OS based on high vs low TOP2A expression (P = 1.6e-11). (B) OS based on high vs low SLC2A1 expression (P < 1e-16). (C) OS based on high vs low TPX2 expression (P < 1e-16). (D) OS based on high vs low ASPM expression (P = 1.4e-11). (E) IHC analysis of TOP2A expression in NSCLC (80X and 800X magnifications). (F) OS of NSCLC patients with high or low TOP2A protein expression (P = 0.0259).