Figure 3. Effects of the active compounds containing the effective components of Epimedium, Astragaoside and Puerarin on the mRNA expression levels of the iron uptake protein including DMT1-with IRE, DMT1-without IRE, TF, TfR1, iron release protein including FPN1, CP, HEPH; iron storage protein Ferritin, including Fth and Ftl1 in the cerebral cortex of AD transgenic mice. All data are expressed as the mean ± SD. Inter group differences were compared with multivariate analysis of variance followed by the least significant difference test. (A) P < 0.05, vs. C57; (B) P < 0.05, vs. AD model; (C) P < 0.05, vs. DFO; (D) P < 0.05, vs. Active compounds; (E) P < 0.05, vs. Epimedium; (F) P < 0.05, vs. Astragaoside, P < 0.05, vs. Puerarin.